strange rat behavior?

  i have had my male rat Fenrir for a year now. he has always been sweet and loving and loves to lick my hands. he has never nipped me even in his cage but for about the past 2 months ive been wary about getting him out. once hes out and runs around on my bed for even a minute, he breathes real heavy and snorts and scurrys around like hes running from something and gets rough with my hands. if i just hold him while hes out he stays calm and just licks my hands and sits on my shoulder like normal. but today when i got him out and let him down on my bed he bit me HARD and drew a good bit of blood. i love him and i know hes not doing this maliciously, but i cant figure out why hes acting this way, do you know?
Your best bet would be to e-mail or call Kat Lovings of Rat Dippity Rattery. Just google her website and you will find her contact info. Anyways she is an expert in rat behavior. My only guesses would be that A. there is something in the environment bothering him and causing him to breath hard & act aggressively or B. as he has aged he has developed a hormone inbalance. Hope this helps and if you contact Kat tell her that Dina recommended her:)
Not sure if you will read this or not but I have no other way to contact u since the thread closed. Im not sure what you would get without knowing what the parents carry. A good person to ask is 13 Moons Rattery. If you want you can reach me @ blazingflame10@yahoo.com if you have more questions:)

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my hamster bit me before she died but she was a bit shakey too so mayb urs is jus avin a off day mayb its in a bit a pain or scared a summit: s